This medicine may raise the chance of blood clots, a stroke, or a. The pregnancy rate was approximately 1 pregnancy per 100 women-years. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Check with your pharmacist. Call your doctor right away if you have signs of a blood clot like chest pain or pressure; Period (menstrual) changes. General Disorders and Administration Site Conditions: Chest pain, asthenic conditions. Non-linear accumulation (approximately 8 fold) of NG is observed as a result of high-affinity binding to SHBG, which limits its biological activity (Table 3). Unscheduled Bleeding and Spotting What should I tell my healthcare provider before taking Mili? Mili® (norgestimate and ethinyl estradiol tablets USP) 0.250 mg/0.035 mg Each dark blue coated tablet contains norgestimate may need to be stopped before certain types of surgery as your doctor has told you. Take with or without food. Take Mili (ethinyl estradiol and norgestimate) at the same time of day. Immune System Disorders: Hypersensitivity; There are two ways to start taking birth control pills, Sunday Start or Day 1 Start. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. A past history of COC-related cholestasis predicts an increased risk with subsequent COC use. Anytime you start the pills later than directed, protect yourself by using another method of birth control until you have taken a pill a day for seven consecutive days. It contains 2 hormones: a progestin and an estrogen. Talk with the doctor. NGM is extensively metabolized by first-pass mechanisms in the gastrointestinal tract and/or liver. This medicine does not stop the spread of diseases like. Colesevelam: Colesevelam, a bile acid sequestrant, given together with a COC, has been shown to significantly decrease the AUC of EE. diseases. Your healthcare professional will tell you which to use. Do not use in children who have not had their first menstrual period. This usually is not a serious problem. Arterial Events: Arterial thromboembolism, myocardial infarction, cerebrovascular accident; Steady-state concentration of EE is achieved by Day 7 of each dosing cycle. | ETHINYL ESTRADIOL; NORGESTIMATE (ETH in il es tra DYE ole; nor JES ti mate) is an oral contraceptive. Mili is a birth control medication which contains a combination of 2 hormones, norgestimate and ethinyl estradiol, that are used to prevent ovulation. Some women may miss a period. This risk increases with age and the number of cigarettes you smoke. The use of contraceptive steroids may influence the results of certain laboratory tests, such as coagulation factors, lipids, glucose tolerance, and binding proteins. Additional Information Birth control type. Unscheduled (breakthrough or intracyclic) bleeding and spotting sometimes occur in patients on COCs, especially during the first three months of use. Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin, rufinamide, aprepitant, and products containing St. John’s wort. Following administration of 14C-norgestimate, 47% (45 to 49%) and 37% (16 to 49%) of the administered radioactivity was eliminated in the urine and feces, respectively. Absorption Acute or chronic disturbances of liver function may necessitate the discontinuation of COC use until markers of liver function return to normal and COC causation has been excluded. Human immunodeficiency virus (HIV)/Hepatitis C virus (HCV) protease inhibitors and non-nucleoside reverse transcriptase inhibitors: General information about the safe and effective use of Mili. Carton of 6 Blister Packs packaged in mono cartons NDC 65862-776-86, Carton of 1 Pouch NDC 65862-776-87 When you have picked the right sticker, throw away the others and place the sticker on the blister pack over the preprinted days of the week and make sure it lines up with the pills. Substances decreasing the plasma concentrations of COCs: Substances increasing the plasma concentrations of COCs. 4. Equivalent medications eyes; fever with chills; Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Quantity. Quantity. An additional method of contraception is not needed if Mili is started immediately. You do not need to use a back-up birth control method if you have sex. Refer to the sample of the blister pack below: 3. Use of COCs also increases the risk of arterial thromboses such as strokes and myocardial infarctions, especially in women with other risk factors for these events. Distributed by: If feasible, stop Mili at least 4 weeks before and through 2 weeks after major surgery or other surgeries known to have an elevated risk of VTE as well as during and following prolonged immobilization. Always finish all your pills. What are the possible serious side effects of Mili? In women with hereditary angioedema, exogenous estrogens may induce or exacerbate symptoms of angioedema. Aurobindo Pharma Limited Hyderabad-500 038, India NGMN is bound to albumin and not to SHBG, while NG is bound primarily to SHBG. Many women use birth control pills as their go-to method of contraception. Mili is a combination oral contraceptive containing the progestational compound norgestimate and the estrogenic compound ethinyl estradiol. General information about the safe and effective use of. Ear and Labyrinth Disorders: Vertigo; Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts, and also treat acne. ANALYSIS(65862-776), MANUFACTURE(65862-776). When should I start taking Mili? When you or your teen are ready, learn as much as possible about the various options available for teen birth control. Mili and you have not used a hormonal birth control method before: Mili and you are switching from another birth control pill: Mili and previously used a vaginal ring or transdermal patch: Mili and you are switching from a progestin-only method such as an implant or injection: Mili and you are switching from an intrauterine device or system (IUD or IUS): If you have any questions or are unsure about the information in this leaflet, call your healthcare provider. No increased risk of thromboembolic disease occurring prior to use the Sunday start you. 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